| SM Baker, CJH Davitt, N Motyka, NL Kikendall, K Russel-Lodrigue, CJ Roy, LA Morici |
Burkholderia mallei |
2017 |
1 |
SM Baker, CJH Davitt, N Motyka, NL Kikendall, K Russel-Lodrigue, CJ Roy, and LA Morici. (2017). A Burkholderia pseudomallei Outer Membrane Vesicle Vaccine Provides Cross Protection against Inhalational Glanders in Mice and Non-Human Primates. Vaccines 5:49 https://doi.org/10.3390/vaccines5040049. |
| JS Woodworth, SB Cohen, AO Moquche, CR Plumlee, EM Agger, KB Urdahl, P Andersen |
Mycobacterium tuberculosis |
2017 |
2 |
JS Woodworth, SB Cohen, AO Moquche, CR Plumlee, EM Agger, KB Urdahl, and P Andersen. (2017). Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung. Mucosal Immunology 10(2):555 https://doi.org/10.1038/mi.2016.70. |
| JA Belser, JA Pulit-Penaloza, X Sun, N Brock, C Pappas, HM Creager, H Zeng, TM Tumpey, TR Maines |
Influenza |
2017 |
3 |
JA Belser, JA Pulit-Penaloza, X Sun, N Brock, C Pappas, HM Creager, H Zeng, TM Tumpey, and TR Maines. (2017). A Novel A(H7N2) Influenza Virus Isolated from a Veterinarian Caring for Cats in a New York City Animal Shelter Causes Mild Disease and Transmits Poorly in the Ferret Model. Journal of Virology 91:e00672 https://doi.org/10.1128/JVI.00672-17. |
| HS Heine, SV Shadomy, AE Boyer, L Chuvala, R Riggins, A Kesterson, J Myrick, J Craig, MG Candela, JR Barr, K Hendricks, WA Bower, H Walke, GL Drusano |
Bacillus anthracis |
2017 |
4 |
HS Heine, SV Shadomy, AE Boyer, L Chuvala, R Riggins, A Kesterson, J Myrick, J Craig, MG Candela, JR Barr, K Hendricks, WA Bower, H Walke, and GL Drusano. (2017). Evaluation of combination drug therapy for treatment of antibiotic-resistant inhalation anthrax in a murine model. Antimicrobial Agents and Chermotherapy 61:e00788 https://doi.org/10.1128/AAC.00788-17. |
| HM Creager, J Zeng, JA Pulit-Penaloza, TR Maines, TM Tumpey, JA Belser |
Influenza |
2017 |
5 |
HM Creager, J Zeng, JA Pulit-Penaloza, TR Maines, TM Tumpey, and JA Belser. (2017). In vitro exposure system for study of aerosolized influenza virus. Virology 500:62 https://doi.org/10.1016/j.virol.2016.10.007. |
| ER Wonderlich, AL Hartman, JL Flynn, KS Cole, DS Reed |
Influenza |
2017 |
6 |
ER Wonderlich, AL Hartman, JL Flynn, KS Cole, DS Reed, et al. (2017). Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. Journal of Immunology 198(4):1616 https://doi.org/10.4049/jimmunol.1601770. |
| RJ Fischer, T Bushmaker, S Judson, VJ Munster |
Ebolavirus |
2016 |
7 |
RJ Fischer, T Bushmaker, S Judson, and VJ Munster. (2016). Comparison of the Aerosol Stability of 2 Strains of Zaire ebolavirus From the 1976 and 2013 Outbreaks. Journal of Infectious Diseases 214:S290 https://doi.org/10.1093/infdis/jiw193. |
| RF Johnson, DA Hammoud, DL Perry, J Solomon, IN Moore, MG Lackemeyer, JK Bohannon, PJ Sayre, M Minai, AB Papaneri, KR Hagen, KB Janosko, C Jett, K Cooper, JE Blaney, PB Jahrling |
Poxvirus |
2016 |
8 |
RF Johnson, DA Hammoud, DL Perry, J Solomon, IN Moore, MG Lackemeyer, JK Bohannon, PJ Sayre, M Minai, AB Papaneri, KR Hagen, KB Janosko, C Jett, K Cooper, JE Blaney, and PB Jahrling. (2016). Exposure of rhesus monkeys to cowpox virus Brighton Red by Large-particle aerosol droplets results in an upper respiratory tract disease. Journal of General Virology 97:1942 https://doi.org/10.1099/jgv.0.000501. |
| HS Heine, L Chuvala, R Riggins, R Cirz, R Cass, A Louie, GL Drusano |
Francisella tularensis |
2016 |
9 |
HS Heine, L Chuvala, R Riggins, R Cirz, R Cass, A Louie, and GL Drusano. (2016). Natural History of Francisella tularensis in Aerosol-Challenged BALB/c Mice. Antimicrobial Agents and Chemotherapy 60:1834 https://doi.org/10.1128/AAC.02887-15. |
| E Stinson, LP Smith, KS Cole, EM Barry, DS Reed |
Francisella tularensis |
2016 |
10 |
E Stinson, LP Smith, KS Cole, EM Barry, and DS Reed. (2016). Respiratory and oral vaccination improves protection conferred by the live vaccine strain against pneumonic tularemia in the rabbit model. Pathogens and Disease 74(7):ftw079 https://doi.org/10.1093/femspd/ftw079. |
| CN Propst, AO Nwabueze, IL Kanev, RE Pepin, BW Gutting, VN Morozov, ML van Hoek |
Francisella tularensis |
2016 |
11 |
CN Propst, AO Nwabueze, IL Kanev, RE Pepin, BW Gutting, VN Morozov, and ML van Hoek. (2016). Nanoaerosol reduced required effective dose of liposomal levofloxacin against pulmonary murine Francisella tularensis susp. novicida infection. Journal of Nanobiotechnology 14:29 https://doi.org/10.1186/s12951-016-0182-0. |
| AM Cadena, EC Klein, AG Whilte, JA Tomko, CL Chedrick, DS Reed, LE Via, PL Lin, JL Flynn |
Mycobacterium tuberculosis |
2016 |
12 |
AM Cadena, EC Klein, AG Whilte, JA Tomko, CL Chedrick, DS Reed, LE Via, PL Lin, and JL Flynn. (2016). Very Low Doses of Mycobacterium tuberculosis Yield Diverse Hose Outcomes in Common Marmosets (Tallithrix jacchus). Comparative Medicine 66(5): 1. |
| SJ Smither, M Nelson, L Eastaugh, A Nunez, FJ Salguero, MS Lever |
Ebolavirus |
2015 |
13 |
SJ Smither, M Nelson, L Eastaugh, A Nunez, FJ Salguero, and MS Lever. (2015). Experimental Respiratory Infection of Marmosets (Callithrix jacchus) With Ebola Virus Kikwit. Journal of Infectious Diseases 212:S336 https://doi.org/10.1093/infdis/jiv371. |
| RF Johnson, DA Hammoud, MG Lackemeyer, S Yellayi, J Solomon, JK Bohannon, KB Janosko, C Jett, K Cooper, JE Blaney, PB Jahrling |
Poxvirus |
2015 |
14 |
RF Johnson, DA Hammoud, MG Lackemeyer, S Yellayi, J Solomon, JK Bohannon, KB Janosko, C Jett, K Cooper, JE Blaney, and PB Jahrling. (2015). Small particle aerosol inoculation of cowpox Brighton Red in rhesus monkeys results in a severe respiratory disease. Virology 481:124 https://doi.org/10.1016/j.virol.2015.02.044. |
| JK Bohannon, MG Lackemeyer, JH Kuhn, J Wada, L Bollinger, PB Jahrling, RF Johnson |
Miscellaneous |
2015 |
15 |
JK Bohannon, MG Lackemeyer, JH Kuhn, J Wada, L Bollinger, PB Jahrling, and RF Johnson. (2015). Generation and characterization of large-particle aerosols using a center flow tangential aerosol generator with a non-human-primate, head-only aerosol chamber. Inhalation Toxicology 27(5):247 https://doi.org/10.3109/08958378.2015.1033570. |
| AG Torres, AG Gregory, CL Hatcher, H Vinet-Oliphant, LA Morici, RW Titball, CJ Roy |
Burkholderia mallei |
2015 |
16 |
AG Torres, AG Gregory, CL Hatcher, H Vinet-Oliphant, LA Morici, RW Titball, and CJ Roy. (2015). Protection of non-human primates against glanders with a gold nanoparticle glycoconjugate vaccine. Vaccine 33:686 https://doi.org/10.1016/j.vaccine.2014.11.057. |
| S Massey, LA Yeager, CA Blumentritt, S Vijayakumar, E Sabrana, JW Peterson, T Brasel, JW LeDuc, JJ Endsley, AG Torres |
Burkholderia pseudomallei |
2014 |
17 |
S Massey, LA Yeager, CA Blumentritt, S Vijayakumar, E Sabrana, JW Peterson, T Brasel, JW LeDuc, JJ Endsley, and AG Torres. (2014). Comparative Burkholderia pseudomallei natural history virulence studies using an aerosol murine model of infection. Scientific Reports 4:4305, doi:10.1038/srep04305 https://doi.org/10.1038/srep04305. |
| JS Woodworth, CS Aagaard, PR Hansen, JP Cassidy, EM Agger, and P Andersen. (2014). |
Mycobacterium tuberculosis |
2014 |
19 |
JS Woodworth, CS Aagaard, PR Hansen, JP Cassidy, EM Agger, and P Andersen. (2014). Protective CD4 T Cells Targeting Cryptic Epitopes of Mycobacterium tuberculosis Resist Infection-Driven Terminal Differentiation. Journal of Immunology 192:3247 https://doi.org/10.4049/jimmunol.1300283. |
| PB Jahrling, L Keith, M St. Claire, RF Johnson, L Bollinger, MG Lackemeyer, LE Hensley, J Kindrachuk, JH Kuhn |
Miscellaneous |
2014 |
20 |
PB Jahrling, L Keith, M St. Claire, RF Johnson, L Bollinger, MG Lackemeyer, LE Hensley, J Kindrachuk, and JH Kuhn. (2014). The NIAID Integrated Research Facility at Frederick, Maryland: a unique international resource to facilitate medical countermeasure development for BSL-4 pathogens. Pathogens and Disease 17:211 https://doi.org/10.1111/2049-632X.12171. |
| NPH Knudsen, S Norskov-Lauritsen, GM Dolganov, GK Schoolnik, T Lindenstrom, P Andersen, EM Agger, C Aagaard |
Mycobacterium tuberculosis |
2014 |
22 |
NPH Knudsen, S Norskov-Lauritsen, GM Dolganov, GK Schoolnik, T Lindenstrom, P Andersen, EM Agger, and C Aagaard. (2014). Tuberculosis vaccine with high predicted population coverage and compatibility with modern diagnostics. Proceedings of the National Academy of Sciences, doi10:1073/pnas.1314973111 https://doi.org/10.1073/pnas.1314973111. |
| MV Bianco, S Clark, FC Blanco, S Garbaccio, E Garcia, AA Cataldi, A Williams, F Bigi |
Mycobacterium bovis |
2014 |
24 |
MV Bianco, S Clark, FC Blanco, S Garbaccio, E Garcia, AA Cataldi, A Williams, and F Bigi. (2014). Assessment of Mycobacterium bovis Deleted in p27-p55 Virulence Operon as Candidate Vaccine against Tuberculosis in Animal Models. BioMed Research International 2014, article ID 951978 https://doi.org/10.1155/2014/951978. |
| MG Lackemeyer, F de Kok-Mercado, J Wada, L Bollinger, J Kindrachuk, V Wahl-Jensen, JH Huhn, PB Jahrling |
Miscellaneous |
2014 |
26 |
MG Lackemeyer, F de Kok-Mercado, J Wada, L Bollinger, J Kindrachuk, V Wahl-Jensen, JH Huhn, and PB Jahrling. (2014). ABSL-4 Aerobiology Biosafety and Technology at the NIH/NIAID Integrated Research Facility at Fort Detrick. Viruses 6:137-150; doi:10.3390/v6010137 https://doi.org/10.3390/v6010137. |
| M Bhaskaran, PJ Didier, SK Sivasubramani, LA Doyle, J Holley, CJ Roy |
Ricin |
2014 |
28 |
M Bhaskaran, PJ Didier, SK Sivasubramani, LA Doyle, J Holley, and CJ Roy. (2014). Pathology of lethal and sublethal doses of aerosolized ricin in rhesus macaques. Toxicologic Pathology 42(3):573 https://doi.org/10.1177/0192623313492248. |
| JA Skinner, SM Zurawski, C Sugimoto, H Vinet-Oliphant, P Vinod, Y Xue, K Russel-Lodrigue, RA Albrecht, A Garcia-Sastre, AM Salazar, CJ Roy, MJ Kuroda, SK Oh, G Surawski |
Influenza |
2014 |
30 |
JA Skinner, SM Zurawski, C Sugimoto, H Vinet-Oliphant, P Vinod, Y Xue, K Russel-Lodrigue, RA Albrecht, A Garcia-Sastre, AM Salazar, CJ Roy, MJ Kuroda, SK Oh, and G Surawski. (2014). Immunologic Characterization of a Rhesus Macaque H1N1 Challenge Model for Candidate Influenza Virus Vaccine Assessment. Clinical and Vaccine Immunology 21:1668 https://doi.org/10.1128/CVI.00547-14. |
| JA Belser, KM Gustin, JM Katz, TR Maines, TM Tumpey |
Influenza |
2014 |
31 |
JA Belser, KM Gustin, JM Katz, TR Maines, and TM Tumpey. (2014). Influenza virus infectivity and virulence following ocular-only aerosol inoculation of ferrets. Journal of Virology 88:9647 https://doi.org/10.1128/JVI.01067-14. |
| J Bacon, LJ Alderwick, JA Allnutt, E Gabanova, R Watson, KA Hatch, SO Clark, RE Jeeves, A Marriott, E Rayner, H Tolley, G Pearson, G Hall, GS Besra, L Wemisch, A Williams, PD Marsh |
Mycobacterium tuberculosis |
2014 |
33 |
J Bacon, LJ Alderwick, JA Allnutt, E Gabanova, R Watson, KA Hatch, SO Clark, RE Jeeves, A Marriott, E Rayner, H Tolley, G Pearson, G Hall, GS Besra, L Wernisch, A Williams, and PD Marsh. (2014). Non-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular Matrix. PLoS One, 9:e97329 https://doi.org/10.1371/journal.pone.0087329. |
| DS Reed, PJ Glass, RR Bakken, JF Barth, DM Lind, MK Hart, J Rayner, K Alterson, M Custer, J Dudek, G Owens, KI Kamrud, MD Parker, J Smith |
Alphavirus |
2014 |
34 |
DS Reed, PJ Glass, RR Bakken, JF Barth, DM Lind, MK Hart, J Rayner, K Alterson, M Custer, J Dudek, G Owens, KI Kamrud, MD Parker, and J Smith. (2014). Combined alphavirus replicon particle vaccine induces durable and cross-protective immune responses against equine encephalitic viruses. Journal of Virology 88:12077 https://doi.org/10.1128/JVI.01406-14. |
| DS Reed, L Smith, KS Cole, AE Santiago, BJ Mann, EM Parry |
Francisella tularensis |
2014 |
35 |
DS Reed, L Smith, KS Cole, AE Santiago, BJ Mann, and EM Parry. (2014). Live attenuated mutants of Francisella tularensis protect rabbits against aerosol challenge with a virulent type A strain. Infection and Immunity 82:2098 https://doi.org/10.1128/IAI.01498-14. |
| C Majerczyk, L Kinman, T Han, R Bunt, EP Greenberg |
Burkholderia mallei |
2014 |
36 |
C Majerczyk, L Kinman, T Han, R Bunt, and EP Greenberg. (2014). Virulence of Burkholderia mallei Quorun-Sensing Mutants. Infection and Immunity 81:1471 https://doi.org/10.1128/IAI.00048-13. |
| AL Hartman, DS Powell, LM Bethel, AL Caroline, RJ Schmid, T Oury, DS Reed |
Rift Valley Fever |
2014 |
38 |
AL Hartman, DS Powell, LM Bethel, AL Caroline, RJ Schmid, T Oury, and DS Reed. (2014). Aerosolized Rift Valley Fever Virus Causes Fatal Encephalitis in African Green Monkeys and Common Marmosets. Journal of Virology 88:2235 https://doi.org/10.1128/JVI.02341-13. |
| AL Caroline, DS Powell, LM Bethel, TD Oury, DS Reed, AL Hartman |
Rift Valley Fever |
2014 |
40 |
AL Caroline, DS Powell, LM Bethel, TD Oury, DS Reed, and AL Hartman. (2014). Broad spectrum antiviral activity of Favipiravir (T-705): Protection from highly lethal inhalational Rift Valley Fever in Wistar-Furth rats. PLoS Neglected Tropical Diseases 8:e2790 https://doi.org/10.1371/journal.pntd.0002790. |
| N van Doremalen, T Bushmaker, VJ Munster |
MERS |
2013 |
41 |
N van Doremalen, T Bushmaker, and VJ Munster. (2013). Stability of Middle East respiratory syndrome coronavirus (MERS-CoV) under different environmental conditions. European Surveillance, 18(39), pii 20590 https://doi.org/10.2807/1560-7917.es2013.18.38.20590. |
| L Marsay, M Matsumiya, R Tanner, H Poyntz, KL Griffiths, E Stylianou, PD Marsh, A Williams, S Sharpe, H Fletcher, H McShane |
Mycobacterium tuberculosis |
2013 |
42 |
L Marsay, M Matsumiya, R Tanner, H Poyntz, KL Griffiths, E Stylianou, PD Marsh, A Williams, S Sharpe, H Fletcher, and H McShane. (2013). Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis. Tuberculosis 93:551 https://doi.org/10.1016/j.tube.2013.04.007. |
| KM Lee, KB Chiu, HA Sansling, PJ Didier, TA Ficht, AM Arenas-Gamboa, CJ Roy, AG MacLean |
Miscellaneous |
2013 |
43 |
KM Lee, KB Chiu, HA Sansling, PJ Didier, TA Ficht, AM Arenas-Gamboa, CJ Roy, and AG MacLean, (2013). Aerosol-induced brucellosis increases TLR-2 expression and increased complexity in the microanatomy of astroglia in rhesus macaques. Frontiers in Cellular and Infection Microbiology 3:86 https://doi.org/10.3389/fcimb.2013.00086. |
| KM Gustin, JM Katz, TM Tumpey, TR Maines |
Influenza |
2013 |
44 |
KM Gustin, JM Katz, TM Tumpey, and TR Maines. (2013). Comparison of levels of infectious virus in respirable aerosols exhaled by ferrets infected with influenza viruses exhibiting diverse transmissibility phenotypes. Journal of Virology 87:7864 https://doi.org/10.1128/JVI.00719-13. |
| KL Griffiths, E Stylianou, HC Poyntz, GJ Betts, HA Fletcher, H McShane |
Mycobacterium tuberculosis |
2013 |
45 |
KL Griffiths, E Stylianou, HC Poyntz, GJ Betts, HA Fletcher, and H McShane. (2013). Cholera Toxin Enhances Vaccine-Induced Protection against Mycobacterium tuberculosis Challenge in Mice. PloS One 8(10):e78312 https://doi.org/10.1371/journal.pone.0078312. |
| HS Heine, L Chuvala, R Riggins, G Hurteau, R Cirz, R Cass, A Louis, GL Drusano |
Yersinia pestis |
2013 |
46 |
HS Heine, L Chuvala, R Riggins, G Hurteau, R Cirz, R Cass, A Louis, and GL Drusano. (2013). Natural History of Yersinia pestis Pneumonia in Aerosol-Challenged BALB/c Mice. Antimicrobial Agents and Chemotherapy 57:2010 https://doi.org/10.1128/AAC.02504-12. |
| EL Rayner, GR Pearson, GA Hall, RJ Basaraba, F Gleeson, A McIntyre, S Clark, A Williams, MJ Dennis, SA Sharpe |
Mycobacterium tuberculosis |
2013 |
47 |
EL Rayner, GR Pearson, GA Hall, RJ Basaraba, F Gleeson, A McIntyre, S Clark, A Williams, MJ Dennis, and SA Sharpe. (2013). Early Lesions Following Aerosol Infection of Rhesus Macaques (Macaca mulatta) with Mycobacterium tuberculosis Strain H37RV. Journal of Comparative Pathology 149:475 https://doi.org/10.1016/j.jcpa.2013.05.005. |
| E deWit, J Prescott, L Baseler, T Bushmaker, T Thomas, MG Lackemeyer, C Martellaro, S Milne-Price, E Haddock, BL Haagmans, H Feldmann, VJ Munster |
MERS |
2013 |
48 |
E deWit, J Prescott, L Baseler, T Bushmaker, T Thomas, MG Lackemeyer, C Martellaro, S Milne-Price, E Haddock, BL Haagmans, H Feldmann, VJ Munster. (2013). The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Does Not Replicate in Syrian Hamsters. PLoS One 8:e69127 https://doi.org/10.1371/journal.pone.0069127. |
| DJ Springer, D Saini, EJ Byrnes, J Heitman, R Frothingham |
Miscellaneous |
2013 |
49 |
DJ Springer, D Saini, EJ Byrnes, J Heitman, and R Frothingham. (2013). Development of an aerosol model of Cryptococcus reveals humidity as an important factor affecting the viability of Cryptococcus during aerosolization. PLoS One 8:e69804 https://doi.org/10.1371/journal.pone.0069804. |
| A Arbues, Il Aguilo, J Gonzalo-Asensio, D Marinova, S Uranga, E Puentes, C Fernandez, A Parra, PJ Cardona, C vilaplana, V Ausina, A Williams, S Clark, W Malaga, C Guilhot, B Gicquel, C Martin |
Mycobacterium tuberculosis |
2013 |
50 |
A Arbues, JI Aguilo, J Gonzalo-Asensio, D Marinova, S Uranga, E Puentes, C Fernandez, A Parra, PJ Cardona, C vilaplana, V Ausina, A Williams, S Clark, W Malaga, C Guilhot, B Gicquel, and C Martin. (2013). Construction, characterization, and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials. Vaccine 31:4867 https://doi.org/10.1016/j.vaccine.2013.07.051. |
| JM Bales, DS Powell, LM Bethel, DS Reed, AL Hartman |
Rift Valley Fever |
2012 |
51 |
JM Bales, DS Powell, LM Bethel, DS Reed, and AL Hartman. (2012). Choice of inbred rat strain impacts lethality and disease course after respiratory infection with Rift Valley Fever Virus. Frontiers in Cellular and Infection Microbiology 2:105 https://doi.org/10.3389/fcimb.2012.00105. |
| D Saini, GW Hopkins, SA Sea, CJ Chen, CC Perley, EM Click, R Frothingham |
Mycobacterium tuberculosis |
2012 |
52 |
D Saini, GW Hopkins, SA Sea, CJ Chen, CC Perley, EM Click, and R Frothingham. (2012). Ultra-low dose of Mycobacterium tuberculosis aerosol creates partial infection in mice. Tuberculosis 92:160 https://doi.org/10.1016/j.tube.2011.11.007. |
| AC Shurtleff, N Garza, M Lackemeyer, R Carrion, A Griffiths, J Patterson, SS Edwin, S Bavari |
Miscellaneous |
2012 |
53 |
AC Shurtleff, N Garza, M Lackemeyer, R Carrion, A Griffiths, J Patterson, SS Edwin, and S Bavari. (2012). The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainment. Viruses 4:3932 https://doi.org/10.3390/v4123932. |
| SA Faith, LP Smith, AS Swatland, DS Reed |
Francisella tularensis |
2012 |
54 |
SA Faith, LP Smith, AS Swatland, and DS Reed. (2012). Growth conditions and environmental factors impact aerosolization but not virulence of Fracisella tularensis infection in mice. Frontiers in Cellular and Infection Microbiology 2:126 https://doi.org/10.3389/fcimb.2012.00126. |
| KM Gustin, JA Belser, DA Wadford, MB Pearce, JM Katz, TM Tumpey, TR Maines |
Influenza |
2011 |
56 |
KM Gustin, JA Belser, DA Wadford, MB Pearce, JM Katz, TM Tumpey, and TR Maines. (2011). Influenza virus aerosol exposure and analytical system for ferrets. Proceedings of the National Academy of Science 108(20):8432 https://doi.org/10.1073/pnas.1100768108. |
| Reed, L Smith, T Dunsmore, A Trichel, LA Ortiz, KS Cole, E Barry |
Francisella tularensis |
2011 |
57 |
DS Reed, L Smith, T Dunsmore, A Trichel, LA Ortiz, KS Cole, and E Barry. (2011). Pneumonic Tularemia in Rabbits Resembles the Human Disease as Illustrated by Radiographic and Hematological Changes after Infection. PLoS One 6(9): e24654 https://doi.org/10.1371/journal.pone.0024654. |
| D Saini, GW Hopkins, C Chen, SA Seay, EM Click, S Lee, JM Hartings, R Frothingham |
Miscellaneous |
2011 |
58 |
D Saini, GW Hopkins, C Chen, SA Seay, EM Click, S Lee, JM Hartings, and R Frothingham. (2011). Sampling port for real-time analysis of bioaerosol in whole body exposure system for animal aerosol model development. Journal of Pharmacological and Toxicological Methods 63:143 (2011) https://doi.org/10.1016/j.vascn.2010.09.002. |
| P Fellows, J Adamovicz, JM Hartings, R Sherwood, W Mega, T Brasel, E Barr, L Holland, W Lin, A Rom, W Blackwelder, J Price, S Morris, D Snow, MK Hart |
Yersinia pestis |
2010 |
59 |
P Fellows, J Adamovicz, JM Hartings, R Sherwood, W Mega, T Brasel, E Barr, L Holland, W Lin, A Rom, W Blackwelder, J Price, S Morris, D Snow, and MK Hart. (2010). Protection in mice passively immunized with serum from cynomolgus macaques and humans vaccinated with recombinant plague vaccine (rF IV). Vaccine 28:7748 https://doi.org/10.1016/j.vaccine.2010.09.062. |
| A Nalca, VA Livingston, NL Garza, EE Zumbrun, OM Frick, JL Chapman, JM Hartings |
Poxvirus |
2010 |
60 |
A Nalca, VA Livingston, NL Garza, EE Zumbrun, OM Frick, JL Chapman, and JM Hartings. (2010). Experimental infection of Cynomologus Macaques (Macaca fascicularis) with aerosolized Monkeypox Virus. PLoS One 5:e12880 https://doi.org/10.1371/journal.pone.0012880. |
| BKL Sim, M Li, M Osorio, Y Wu, TT Wai, JW Peterson, ER James, S Chakravarty, L Gao, R Xu, N KC, RE Stafford, WS Lawrence, LA Yeager, JE Peel, SK Sivasubramani, AK Chopra, S Filippova, and SL Hoffman |
Bacillus anthracis |
2017 |
61 |
BKL Sim, M Li, M Osorio, Y Wu, TT Wai, JW Peterson, ER James, S Chakravarty, L Gao, R Xu, N KC, RE Stafford, WS Lawrence, LA Yeager, JE Peel, SK Sivasubramani, AK Chopra, S Filippova, and SL Hoffman. (2017). Protection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis. NPJ Vaccines 2:17 https://doi.org/10.1038/s41541-017-0018-4. |
| R Billeskov, T Lindenstrom, J Woodworth, C Filaplana, PJ Cardona, HP Cassidy, R Mortensen, EM Agger, and P Andersen |
Mycobacterium tuberculosis |
2018 |
62 |
R Billeskov, T Lindenstrom, J Woodworth, C Filaplana, PJ Cardona, HP Cassidy, R Mortensen, EM Agger, and P Andersen. (2018). High Antigen Dose Is Detrimental to Post-Exposure Vaccine Protection against Tuberculosis. Frontiers in Immunology 8:1973 https://doi.org/10.3389/fimmu.2017.01973. |
| R Harrington-Kandt, E Stylianou, LA Eddowes, PJ Lim, L Stockdale, N Pinpathomrat, N Bull, J Pasricha, M Ulaszewska, Y Beglov, S Faulont, H Drakesmith, and H McShane |
Mycobacterium tuberculosis |
2018 |
63 |
R Harrington-Kandt, E Stylianou, LA Eddowes, PJ Lim, L Stockdale, N Pinpathomrat, N Bull, J Pasricha, M Ulaszewska, Y Beglov, S Faulont, H Drakesmith, and H McShane. (2018). Hipcidin deficiency and iron deficiency do not alter tuberculosis susceptibility in a murine M. tb infection model. PLoS One 13(1):e0191038 https://doi.org/10.1371/journal.pone.0191038. |
| HM Creager, A Kumar, J Zeng, TR Maines, TM Tumpey, and JA Belser |
Influenza |
2018 |
64 |
HM Creager, A Kumar, J Zeng, TR Maines, TM Tumpey, and JA Belser. (2018). Infection and Replication of Influenza Virus at the Ocular Surface. Journal of Virology 92:e02192-17 https://doi.org/10.1128/JVI.02192-17. |
| P Hart, A Copland, GR Diogo, S Harris, R Spallek, W Oehlmann, M Singh, J Basile, M Rottenberg, MJ Paul, R Relji |
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| A Copland, GR Diogo, P Hart, S Harris, AC Tran, MJ Paul, M Singh, SM Cutting, and R Reljic |
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| T Lindenstrom, A Moguche, M Damborg, EM Agger, K Urdahl, and P Andersen |
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T Lindenstrom, A Moguche, M Damborg, EM Agger, K Urdahl, and P Andersen. (2018). T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties. EBioMedicine 27:17 https://doi.org/10.1016/j.ebiom.2017.12.004. |
| DA Hammoud, MR Lentz, A Lara, JK Bohannon, I Feuerstein, L Huzella, PB Jahrling, M Lackemeyer, J Laux, O Rojas, P Sayre, J Solomon, Y Cong, V Munster, and MR Holgrook |
Nipah |
2018 |
68 |
DA Hammoud, MR Lentz, A Lara, JK Bohannon, I Feuerstein, L Huzella, PB Jahrling, M Lackemeyer, J Laux, O Rojas, P Sayre, J Solomon, Y Cong, V Munster, and MR Holgrook. (2018). Aerosol exposure to intermediate size Nipah virus particles induces neurological disease in African green monkeys. PLOS Neglected Tropical Diseases https://doi.org/10.1371/journal.pntd.0006978. |
| O Escaffre, T Hill, T Ikegami, TL Juelich, JK Smith, L Zhang, DE Perez, C Atkins, A Park, WS Lawrence, SK Sivasubramani, JE Peel, JW Peterson, B Lee and AN Frieberg |
Nipah |
2018 |
69 |
O Escaffre, T Hill, T Ikegami, TL Juelich, JK Smith, L Zhang, DE Perez, C Atkins, A Park, WS Lawrence, SK Sivasubramani, JE Peel, JW Peterson, B Lee and AN Frieberg. (2018). Experimental Infection of Syrian Hamsters With Aerosolized Nipah Virus. Journal of Infectious Diseases 218:1602 https://doi.org/10.1093/infdis/jiy357. |
| N Khakhum, P Bharaj, JN Myers, D Tapia, PB Kilgore, BN Ross, DH Walker, JJ Endsley, and AG Torres |
Burkholderia pseudomallei |
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70 |
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| JA Pulit-Penaloza, JA Besler, TM Tumpey, and TR Maines |
Influenza |
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71 |
JA Pulit-Penaloza, JA Besler, TM Tumpey, and TR Maines. (2019). Swine-Origin H1 Influenza Viruses Isolated from Humans Exhibit Sustained Infectivity in an Aerosol State. Applied and Environmental Microbiology 85:1 https://doi.org/10.1128/AEM.00210-19. |
| JS Woodworth, D Christensen, JP Cassidy, EM Agger, R Mortensen, and P Andersen |
Mycobacterium Tuberculosis |
2019 |
72 |
JS Woodworth, D Christensen, JP Cassidy, EM Agger, R Mortensen, and P Andersen. (2019). Mucosal boosting of H56:CAF01 Immunization promotes lung-localized T cells and an accelerated pulmonary response to Mycobacterium tuberculosis infection without enhancing vaccine protection. Mucosal Immunology 12(3):816 https://doi.org/10.1038/s41385-019-0145-5. |
| SL Dahl, JS Woodworth, CJ Lerche, EP Cramer, PR Nielsen, C Moser, AR Thomsen, N Borregaard, and JB Cowland |
Mycobacterium tuberculosis |
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73 |
SL Dahl, JS Woodworth, CJ Lerche, EP Cramer, PR Nielsen, C Moser, AR Thomsen, N Borregaard, and JB Cowland. (2018). Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis. Frontiers in Immunology 9:2717 https://doi.org/10.3389/fimmu.2018.02717. |
| HS Clemmensen, NPH Knudsen, EM Rasmussen, J Winkler, I Rosenkrands, A Ahmad, T Lillebaek, DR Sherman, PL Andersen, and C Aagaard |
Mycobacterium tuberculosis |
2017 |
74 |
HS Clemmensen, NPH Knudsen, EM Rasmussen, J Winkler, I Rosenkrands, A Ahmad, T Lillebaek, DR Sherman, PL Andersen, and C Aagaard. (2017). An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology. Scientific Reports 7:46666 https://doi.org/10.1038/srep46666. |
| Y Cong, MR Lentz, A Lara, I Alexander, C Bartos, JK Bohannon, D Hammoud, L Huzella, PB Jahrling, K Janosko, C Jett, E Kollins, M Lackemeyer, D Mollura, D Ragland, O Rojas, J Solomon, Z Xu, V Munster, and MR Holbrook |
Nipah |
2017 |
75 |
Y Cong, MR Lentz, A Lara, I Alexander, C Bartos, JK Bohannon, D Hammoud, L Huzella, PB Jahrling, K Janosko, C Jett, E Kollins, M Lackemeyer, D Mollura, D Ragland, O Rojas, J Solomon, Z Xu, V Munster, and MR Holbrook. (2017). Loss in lung volume and changes in the immune response demonstrate disease progression in African green monkeys infected by small-particle aerosol and intratracheal exposure to Nipah virus. PLOS Neglected Tripical Diseases https://doi.org/10.1371/journal.pntd.0005532. |
| AN Prasad, KN Agans, SK Sivasubramani, JB Geisbert, V Borisevich, CE Mire, WS Lawrence, KA Fenton, and TW Geisbert |
Nipah |
2019 |
77 |
AN Prasad, KN Agans, SK Sivasubramani, JB Geisbert, V Borisevich, CE Mire, WS Lawrence, KA Fenton, and TW Geisbert. (2019). A Lethal Aerosol Exposure Model of Nipah Virus Strain Bangladesh in African Green Monkeys. Journal of Infectious Diseases https://doi.org/10.1093/infdis/jiz469. |
| JH Lee, DA Hammoud, Y Cong, LM Huzella, MA Castro, J Solomon, J Laux, M Lackemeyer, JK Bohannon, O Rojas, R Byrum, R Adams, D Ragland, M St. Claire, V Munster, and MR Holbrook |
Nipah |
2019 |
78 |
JH Lee, DA Hammoud, Y Cong, LM Huzella, MA Castro, J Solomon, J Laux, M Lackemeyer, JK Bohannon, O Rojas, R Byrum, R Adams, D Ragland, M St. Claire, V Munster, and MR Holbrook. (2019). The Use of Large-Particle Aerosol Exposure to Nipah Virus to Mimic Human Neurological Disease Manifestations in the African Green Monkey. Journal of Infectious Diseases https://doi.org/10.1093/infdis/jiz502. |
| R Hernandez-Pando, SJ Shin, S Clark, S Casonato, M Becerril-Zambrano, H Kim, F Boldrin, D Mata-Espinoza, R Provvedi, A Arbues, B Marquina-Castillo, L Cioetto Mazzabò, J Barrios-Payan, C Martin, SN Cho , A Williams, and R Manganelli |
Mycobacterium tuberculosis |
2019 |
79 |
R Hernandez-Pando, SJ Shin, S Clark, S Casonato, M Becerril-Zambrano, H Kim, F Boldrin, D Mata-Espinoza, R Provvedi, A Arbues, B Marquina-Castillo, L Cioetto Mazzabò, J Barrios-Payan, C Martin, SN Cho , A Williams, and R Manganelli. (2019). Construction and Characterization of the Mycobacterium tuberculosis sigE fadD26 Unmarked Double Mutant as a Vaccine Candidate. Infection and Immunity 88(1):e00496 https://doi.org/10.1128/IAI.00496-19. |
| A Chandran, K Williams, T Mendum, G Stewart, S Clark, S Zadi, N McLeod, A Williams, B Villarreal-Ramos, M Vordermeier, V Maroudam, A Prasad, N Bharti, R Banerjee, S Manjari Kasibhatla, and J McFadden |
Mycobacterium bovis |
2019 |
80 |
A Chandran, K Williams, T Mendum, G Stewart, S Clark, S Zadi, N McLeod, A Williams, B Villarreal-Ramos, M Vordermeier, V Maroudam, A Prasad, N Bharti, R Banerjee, S Manjari Kasibhatla, and J McFadden. (2019). Development of a diagnostic compatible BCG vaccine against Bovine tuberculosis. Scientific Reports 9(1):17791 https://doi.org/10.1038/s41598-019-54108-y. |
| M Fitzpatrick, MM Ho, S Clark, B Dagg, B Khatri, F Lanni, A Williams, M Brennan, D Laddy, and B Walker |
Mycobacterium tuberculosis |
2019 |
81 |
M Fitzpatrick, MM Ho, S Clark, B Dagg, B Khatri, F Lanni, A Williams, M Brennan, D Laddy, and B Walker. (2019). Comparison of pellicle and shake flask-grown BCG strains by quality control assays and protection studies. Tuberculosis (Edinb) 114:47 https://doi.org/10.1016/j.tube.2018.10.013. |
| G Larrouy-Maumus, E Layre, S Clark, J Prandi, E Rayner, M Lepore, G de Libero, A Williams, G Puzo, and M Gilleron |
Mycobacterium tuberculosis |
2017 |
82 |
G Larrouy-Maumus, E Layre, S Clark, J Prandi, E Rayner, M Lepore, G de Libero, A Williams, G Puzo, and M Gilleron. (2017). Protective efficacy of a lipid antigen vaccine in a guinea pig model of tuberculosis. Vaccine 35(10):1395 https://doi.org/10.1016/j.vaccine.2017.01.079. |
| S Clark, F Lanni, D Marinova, E Rayner, C Martin, and A Williams |
Mycobacterium tuberculosis |
2017 |
83 |
S Clark, F Lanni, D Marinova, E Rayner, C Martin, and A Williams. (2017). Revaccination of Guinea Pigs With the Live Attenuated Mycobacterium tuberculosis Vaccine MTBVAC Improves BCG's Protection Against Tuberculosis. Journal of Infectious Diseases. 216(5):525 https://doi.org/10.1093/infdis/jix030. |
| SA Sharpe, AD White, L Sibley, F Gleeson, GA Hall, RJ Basaraba, A McIntyre, SO Clark, K Gooch, PD Marsh, A Williams, and MJ Denni |
Mycobacterium tuberculosis |
2017 |
84 |
SA Sharpe, AD White, L Sibley, F Gleeson, GA Hall, RJ Basaraba, A McIntyre, SO Clark, K Gooch, PD Marsh, A Williams, and MJ Denni. (2017). An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques. PLoS One. 12(3):e0171906 https://doi.org/10.1371/journal.pone.0171906. |
| L Sibley, M Dennis, C Sarfas, A White, S Clark, F Gleeson, A McIntyre, E Rayner, G Pearson, A Williams, P Marsh, S Sharpe |
Mycobacterium tuberculosis |
2016 |
85 |
L Sibley, M Dennis, C Sarfas, A White, S Clark, F Gleeson, A McIntyre, E Rayner, G Pearson, A Williams, P Marsh, and S Sharpe. (2016). Route of delivery to the airway influences the distribution of pulmonary disease but not the outcome of Mycobacterium tuberculosis infection in rhesus macaques. Tuberculosis (Edinb) 96:141 https://doi.org/10.1016/j.tube.2015.11.004. |
| S Sharpe, A White, F Gleeson, A McIntyre, D Smyth, S Clark, C Sarfas, D Laddy, E Rayner, G Hall, A Williams, and M Dennis |
Mycobacterium tuberculosis |
2016 |
86 |
S Sharpe, A White, F Gleeson, A McIntyre, D Smyth, S Clark, C Sarfas, D Laddy, E Rayner, G Hall, A Williams, and M Dennis. (2016). Ultra-low dose aerosol challenge with Mycobacterium tuberculosis leads to divergent outcomes in rhesus and cynomolgus macaques. Tuberculosis (Edinb) 96:1. |
| E Stylianou, KL Griffiths, HC Poyntz, R Harrington-Kandt, MD Dicks, L Stockdale, G Betts, and H McShane |
Mycobacterium tuberculosis |
2015 |
87 |
E Stylianou, KL Griffiths, HC Poyntz, R Harrington-Kandt, MD Dicks, L Stockdale, G Betts, and H McShane. (2015). Improvement of BCG protective efficacy with a novel chimpanzee adenovirus and modified vaccinia Ankara virus both expressing Ag85A. Vaccine 33:6800 https://doi.org/10.1016/j.vaccine.2015.10.017. |
| P Sander, S Clark, A Petrera, C Vilaplana, M Meuli, P Selchow, A Zelmer, D Mohanan, N Andreu, E Rayner, M Dal Molin, GJ Bancroft, P Johansen, PJ Cardona, A Williams, and EC Böttger |
Mycobacterium bovis |
2015 |
88 |
P Sander, S Clark, A Petrera, C Vilaplana, M Meuli, P Selchow, A Zelmer, D Mohanan, N Andreu, E Rayner, M Dal Molin, GJ Bancroft, P Johansen, PJ Cardona, A Williams, and EC Böttger. (2015). Deletion of zmp1 improves Mycobacterium bovis BCG-mediated protection in a guinea pig model of tuberculosis. Vaccine 33(11):1353 https://doi.org/10.1016/j.vaccine.2015.01.058. |
| D Bottai, W Frigui, S Clark, E Rayner, A Zelmer, N Andreu, MI de Jonge, GJ Bancroft, A Williams, P Brodin, and R Brosch |
Mycobacterium tuberculosis |
2015 |
89 |
D Bottai, W Frigui, S Clark, E Rayner, A Zelmer, N Andreu, MI de Jonge, GJ Bancroft, A Williams, P Brodin, and R Brosch. (2015). Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system. Vaccine 33(23):2710 https://doi.org/10.1016/j.vaccine.2015.03.083. |
| SO Clark, G Delogu, E Rayner, M Sali, A Williams , and R Manganelli |
Mycobacterium tuberculosis |
2015 |
90 |
SO Clark, G Delogu, E Rayner, M Sali, A Williams , and R Manganelli. (2015). Improved protection in guinea pigs after vaccination with a recombinant BCG expressing MPT64 on its surface. Trials in Vaccinology 4:29 https://doi.org/10.1016/j.trivac.2015.03.003. |
| S Commandeur, SJ van den Eeden, K Dijkman, SO Clark, KE van Meijgaarden, L Wilson, KL Franken, A Williams, D Christensen, TH Ottenhoff , and A Geluk |
Mycobacterium tuberculosis |
2014 |
91 |
S Commandeur, SJ van den Eeden, K Dijkman, SO Clark, KE van Meijgaarden, L Wilson, KL Franken, A Williams, D Christensen, TH Ottenhoff , and A Geluk. (2014). The in vivo expressed Mycobacterium tuberculosis (IVE-TB) antigen Rv2034 induces CD4⁺ T-cells that protect against pulmonary infection in HLA-DR transgenic mice and guinea pigs. Vaccine 32(29):3580 https://doi.org/10.1016/j.vaccine.2014.05.005. |
| HC Poyntz, E Stylianou, KL Griffiths, L Marsay, AM Checkley, and H McShane |
Mycobacterium tuberculosis |
2014 |
92 |
HC Poyntz, E Stylianou, KL Griffiths, L Marsay, AM Checkley, and H McShane. (2014). Non-tuberculous mycobacteria have diverse effects on BCG efficacy against Mycobacterium tuberculosis. Tuberculosis 94:1-12 https://doi.org/10.1016/j.tube.2013.12.006. |
| DS Reed, LM Bethel, DS Powell, AL Caroline, and AL Hartman |
Rift Valley Fever |
2014 |
93 |
DS Reed, LM Bethel, DS Powell, AL Caroline, and AL Hartman. (2014). Differences in aerosolization of Rift Valley fever virus resulting from choice of inhalation exposure chamber: implications for animal challenge studies. Pathogens and Disease 71(2):227 https://doi.org/10.1111/2049-632X.12157. |
| A Afonso-Barroso, SO Clark, A Williams, GT Rosa, C Nóbrega, S Silva-Gomes, S Vale-Costa, R Ummels, N Stoker, F Movahedzadeh, P van der Ley, A Sloots, M Cot, BJ Appelmelk, G Puzo, J Nigou, J Geurtsen, and R Appelberg |
Mycobacterium tuberculosis |
2013 |
94 |
A Afonso-Barroso, SO Clark, A Williams, GT Rosa, C Nóbrega, S Silva-Gomes, S Vale-Costa, R Ummels, N Stoker, F Movahedzadeh, P van der Ley, A Sloots, M Cot, BJ Appelmelk, G Puzo, J Nigou, J Geurtsen, and R Appelberg. (2013). Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses. Cell Microbiology 15(4):660 https://doi.org/10.1111/cmi.12065. |
| N van Doremalen, T Bushmaker, D Morris, M Holbrook, A Gamble, B Williamson, A Tamin, J Harcourt, N Thornburg, S Gerber, J Lloyd-Smith, E de Wit, and V Munster |
SARS-CoV-2 |
2020 |
95 |
N van Doremalen, T Bushmaker, D Morris, M Holbrook, A Gamble, B Williamson, A Tamin, J Harcourt, N Thornburg, S Gerber, J Lloyd-Smith, E de Wit, and V Munster. (2020). Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1. The New England Journal of Medicine https://doi.org/10.1056/NEJMc2004973. |
| F Levillain, H Kim, Kwon K Woong, S Clark, F Cia F, W Malaga, F Lanni, P Brodin, B Gicquel, C Guilhot, GJ Bancroft, A Williams, Shin S Jae, Y Poquet, and O Neyrolles |
Mycobacterium tuberculosis |
2020 |
96 |
F Levillain, H Kim, Kwon K Woong, S Clark, F Cia F, W Malaga, F Lanni, P Brodin, B Gicquel, C Guilhot, GJ Bancroft, A Williams, Shin S Jae, Y Poquet, and O Neyrolles. (2020). Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis. Vaccine 38(6):1416 https://doi.org/10.1016/j.vaccine.2019.11.085. |
| Henry Ma, J Lundy, K O’Malley, WB Klimstra, AL Hartman, and DS Reed |
Alphavirus |
2019 |
97 |
Henry Ma, J Lundy, K O’Malley, WB Klimstra, AL Hartman, and DS Reed. (2019). Electrocardiography Abnormalities in Macaques after Infection with Encephalitic Alphaviruses. Pathogens 8(4):240 https://doi.org/10.3390/pathogens8040240. |
| JD Bowling, KJ O’Malley, WB Klimstra, AL Hartman, and SD Reed |
Miscellaneous |
2019 |
98 |
JD Bowling, KJ O’Malley, WB Klimstra, AL Hartman, and SD Reed. (2019). A vibrating mesh nebulizer as an alternative to the Collison 3-jet nebulizer for infectious disease aerobiology. Applied and Environmental Microbiology 85(17):e00747-19 https://doi.org/10.1128/AEM.00747-19. |
| J Albe, DA Boyles, AW Walters, MR Kujawa, CM McMillen, DS Reed, and AL Hartman |
Rift Valley Fever |
2019 |
99 |
J Albe, DA Boyles, AW Walters, MR Kujawa, CM McMillen, DS Reed, and AL Hartman. (2019). Neutrophil and macrophage influx into the central nervous system are inflammatory components of lethal Rift Valley Fever encephalitis in rats. PLoS Pathogens 15(6):e1007833 https://doi.org/10.1371/journal.ppat.1007833. |
| K O’Malley, JD Bowling, KRO Hazlett, EM Barry, DS Reed |
Francisella tularensis |
2019 |
100 |
K O’Malley, JD Bowling, KRO Hazlett, EM Barry, and DS Reed. (2019). Development, characterization and standardization of a nose-only inhalation exposure system for exposure of rabbits to small particle aerosols containing Francisella tularensis. Infection & Immunity 87:e00198-19 https://doi.org/10.1128/IAI.00198-19. |
| DW Trobaugh, C Sun, DS Reed, and WB Klimstra |
Alphavirus |
2019 |
101 |
DW Trobaugh, C Sun, DS Reed, and WB Klimstra. (2019). Rational design of a live-attenuated eastern equine encephalitis virus vaccine through informed mutation of virulence determinants. PLoS Pathogens 15(2):e1007584 https://doi.org/10.1371/journal.ppat.1007584. |
| AW Walters, MR Kujawa, JR Albe, DS Reed, WK Klimstra, and AL Hartman |
Rift Valley Fever |
2019 |
102 |
AW Walters, MR Kujawa, JR Albe, DS Reed, WK Klimstra, and AL Hartman. (2019). Widespread vascular breakdown is a late pathogenic event during Rift Valley fever virus encephalitis in rats. Virology. 526:173 https://doi.org/10.1016/j.virol.2018.10.021. |
| AS Kim, SK Austin, CL Gardner, A Zuiani, DS Reed, D Trobaugh, C Sun, K Basore, LE Williamson, JE Crowe, MK Slifka, DH Fremont, WB Klimstra, and MS Diamond |
Alphavirus |
2018 |
103 |
AS Kim, SK Austin, CL Gardner, A Zuiani, DS Reed, D Trobaugh, C Sun, K Basore, LE Williamson, JE Crowe, MK Slifka, DH Fremont, WB Klimstra, and MS Diamond. (2018). Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 protein. Nature Microbiology 4:187 https://doi.org/10.1038/s41564-018-0286-4. |
| K O’Malley, JD Bowling, E Stinson, KS Cole, BJ Mann, P Namjoshi, KRO Hazlett, EM Barry, and DS Reed |
Francisella tularensis |
2018 |
104 |
S Sharpe, A White, F Gleeson, A McIntyre, D Smyth, S Clark, C Sarfas, D Laddy, E Rayner, G Hall, A Williams, and M Dennis. (2016). Ultra-low dose aerosol challenge with Mycobacterium tuberculosis leads to divergent outcomes in rhesus and cynomolgus macaques. Tuberculosis (Edinb) 96:1 https://doi.org/10.1016/j.tube.2015.10.004. |
| RW Gregg, P Maiello, HJ Borish, T Coleman, D Reed, A White, J Flynn, and PL Lin |
Mycobacterium tuberculosis |
2018 |
105 |
RW Gregg, P Maiello, HJ Borish, T Coleman, D Reed, A White, J Flynn, and PL Lin. (2018). Spatial and temporal evolution of lung granulomas in a cynomolgus macaque model of Mycobacterium tuberculosis infection. Radiology of Infectious Diseases 5(3):110 https://doi.org/10.1016/j.jrid.2018.08.001. |
| ER Wonderlich, AL Caroline, CM McMillen, AW Walters, DS Reed, SM Barratt-Boyes, and AL Hartman |
Rift Valley Fever |
2018 |
106 |
ER Wonderlich, AL Caroline, CM McMillen, AW Walters, DS Reed, SM Barratt-Boyes, and AL Hartman. (2018). Peripheral blood biomarkers of disease outcome in a monkey model of Rift Valley Fever encephalitis. Journal of Virology 92(3): e01662-17 https://doi.org/10.1128/JVI.01662-17. |
| AM Watson, A Rose, G Gibson, C Gardner, C Sun, DS Reed, C St. Croix, P Strick, WB Klimstra, and S Watkins |
Alphavirus |
2017 |
107 |
AM Watson, A Rose, G Gibson, C Gardner, C Sun, DS Reed, C St. Croix, P Strick, WB Klimstra, S Watkins. (2017). Ribbon Scanning Confocal for High-Speed High-Resolution Volume Imaging of Brain. PLoS ONE 12(7):e0180486 https://doi.org/10.1371/journal.pone.0180486. |
| KM Holland, SJ Rosa, K Kristjansdottir, D Wolfgeher, B Franz, TM Zarrella, S Kumar, S Sunagar, A Singh, CS Bakshi, EM Barry, TJ Sellati, SJ Kron, EJ Gosselin, DS Reed, and KRO Hazlett |
Francisella tularensis |
2017 |
108 |
KM Holland, SJ Rosa, K Kristjansdottir, D Wolfgeher, B Franz, TM Zarrella, S Kumar, S Sunagar, A Singh, CS Bakshi, EM Barry, TJ Sellati, SJ Kron, EJ Gosselin, DS Reed, and KRO Hazlett. (2017). Differential growth of Francisella tularensis, which alters expression of virulence factors, dominant antigens, and surface-carbohydrate enzymes, governs the efficacy of prophylactic immunization. Frontiers in Cellular and Infection Microbiology 8:1158 https://doi.org/10.3389/fmicb.2017.01158. |
| CL Gardner, C Sun, T Luke, K Raviprakash, H Wu, J Jiao, E Sullivan, DS Reed, KD Ryman, and WB Klimstra |
Alphavirus |
2017 |
109 |
CL Gardner, C Sun, T Luke, K Raviprakash, H Wu, J Jiao, E Sullivan, DS Reed, KD Ryman, and WB Klimstra. (2017). Antibody preparations from human transchromosomic cows exhibit prophylactic and therapeutic efficacy versus Venezuelan equine encephalitis virus. Journal of Virology 91(14):e00226.17 https://doi.org/10.1128/JVI.00226-17. |
| CJ Roy, DJ Ehrbar, N Bohorova, O Bohorov, D Kim, M Pauly, K Whaley, Y Rong, FJ Torres-Velez, ES Vitetta, PJ Didier, L Doyle-Meyers, L Zeitlin, and NJ Mantis |
Ricin |
2019 |
110 |
CJ Roy, DJ Ehrbar, N Bohorova, O Bohorov, D Kim, M Pauly, K Whaley, Y Rong, FJ Torres-Velez, ES Vitetta, PJ Didier, L Doyle-Meyers, L Zeitlin, and NJ Mantis. (2019). Rescue of Rehsus Macaques From Lethality of Aerosolized Ricin Toxin. JCI Insight 4(1):e124771 https://doi.org/10.1172/jci.insight.124771. |
| SY Ko, W Akahata, ES Yang, WP Kong, CW Burke, SP Honnold, DK Nichols, YJS Huang, GL Schieber, K Carlton, L DaSilva, V Traina-Dorge, DL Vanlandingham, Y Tsybovsky, T Stephens, U Baxa, S Higgs, CJ Roy, PJ Glass, JR Mascola, GJ Nabel, and SS Rao |
Alphavirus |
2019 |
111 |
SY Ko, W Akahata, ES Yang, WP Kong, CW Burke, SP Honnold, DK Nichols, YJS Huang, GL Schieber, K Carlton, L DaSilva, V Traina-Dorge, DL Vanlandingham, Y Tsybovsky, T Stephens, U Baxa, S Higgs, CJ Roy, PJ Glass, JR Mascola, GJ Nabel, and SS Rao. (2019). A Virus-Like Particle Vaccine Prevents Equine Encephalitis Virus Invection in Nonhuman Primates. Science Translational Medicine 11(492):eaav3113 https://doi.org/10.1126/scitranslmed.aav3133. |
| MJ Kuroda, C Sugimoto, Y Cai, KM Merino, S Mehra, M Arainga, CJ Roy, CC Midkiff, X Alvarez, ES Didier, and D Kaushal |
Mycobacterium tuberculosis |
2018 |
112 |
MJ Kuroda, C Sugimoto, Y Cai, KM Merino, S Mehra, M Arainga, CJ Roy, CC Midkiff, X Alvarez, ES Didier, and D Kaushal. (2018). High Turnover of Tissue Macrophages Contributes to Tuberculosis Reactivation in Simian Immunodeficiency Virus-Infected Rhesus Macaques. Journal of Infectious Diseases 217(12):1865 https://doi.org/10.1093/infdis/jix625. |
| JD Shearer, ML Saylor, CM Butler, AM Treston, HS Heine, S Chirakul, HP Schweizer, A Louie, GL Drusano, SD Zumbrun, and KL Warfield |
Burkholderia pseudomallei |
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SARS-CoV-2 |
2024 |
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DS Reed, AK McElroy, DJ Barbeau, CM McMillen, NL Tilson-Lunel, S Nambulli, E Cottle, TC Gilliland, H Rannulu, J Lundy, EL Olsen, KJ O’Malley, M Xia, AL Hartman, TC Luke, K Egland, C Bausch, H Wu, EJ Sullivan, WB Klimstra, and WP Duprex. (2004). No evidence for enhanced disease with human polyclonal SARS-CoV-2 antibody in the ferret model. PLoS One 19(6):e0290909 https://doi.org/10.1371/journal.pone.0290909. |
| LJ Adams, S Raju, H Ma, T Gilliland, DS Reed, WB Klimstra, DH Fremont, and MS Diamond |
Alphavirus |
2023 |
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| M Kanekiyo, RA Gillespie, M Midgett, KJ O’Malley, C Williams, SM Moin, M Wallace, L Treaster...BS Graham, SM Barratt-Boyes, and DS Reed |
Influenza |
2023 |
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| M Kaneyiko, RA Gillespie, K Cooper, V Guerra Canedo, PMS Castanha, A Pegu, ES Yang, L Treaster, G Yun, M Wallace, G Kettenburg, C Williams, J Lundy, S Barrick, K O’Malley M Midgett, MM Marti… BS Graham, DS Reed, and SM Barrat-Boyes |
Influenza |
2025 |
164 |
M Kaneyiko, RA Gillespie, K Cooper, V Guerra Canedo, PMS Castanha, A Pegu, ES Yang, L Treaster, G Yun, M Wallace, G Kettenburg, C Williams, J Lundy, S Barrick, K O’Malley M Midgett, MM Marti… BS Graham, DS Reed, and SM Barrat-Boyes. (2025). Pre-exposure antibody prophylaxis protects macaques from severe influenza. Science 387:534 https://doi.org/10.1126/science.ado6481. |
| JS Woodworth, V Contreras, D Christensen, T Naninck, N Kahlaoui, A-S Gallouet, S Langolis, E Burban, C Joly, W Gros... R LeGrand, GK Pedersen, and R Mortensen |
Mycobacterium tuberculosis |
2024 |
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| HS Heine, G Drusano, BK Purcell, D Anastasiou, SK Tanaka, and AW Serio |
Bacillus anthracis |
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| KA Connors, NS Chapman, CM McMillen, RM Hoehl, JJ McGaughey, ZD Frey, M Midgett, C Williams, DS Reed, JE Crowe Jr., and AL Hartman |
Rift Valley Fever |
2024 |
167 |
KA Connors, NS Chapman, CM McMillen, RM Hoehl, JJ McGaughey, ZD Frey, M Midgett, C Williams, DS Reed, JE Crowe Jr., and AL Hartman. (2024). Potent neutralizing human monoclonal antibodies protect from Rift Valley fever encephalitis. JCI Insight 9(18):e180151 https://doi.org/10.1172/jci.insight.180151. |
| D Malouli, M Tiwary, RM Gilbride, DW Morrow, CM Hughes, A Salseth, T Penny, P Castanha, M Wallace, Y Yeung, M Midget, C Williams, J Reed, Y Yu, L Gao, G Yun, L Treaster… DS Reed, and JB Sacha |
Influenza |
2024 |
168 |
D Malouli, M Tiwary, RM Gilbride, DW Morrow, CM Hughes, A Salseth, T Penny, P Castanha, M Wallace, Y Yeung, M Midget, C Williams, J Reed, Y Yu, L Gao, G Yun, L Treaster… DS Reed, and JB Sacha. (2024). Cytomegalovirus vaccine vector-induced effector memory CD4+T cells protect cynomologus macaques from lethal aerosolized heterologous avian influenza challenge. Nature Communications 15:6007 https://doi.org/10.1038/s41467-024-50345-6. |
| LJ Adams, S Raju, H Ma, T Gilliland, Jr., DS Reed, WB Klimstra, DH Fremont, and MS Diamond |
Alphavirus |
2024 |
169 |
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| JA Belser, JA Pulit-Penaloza, N Brock, X Sun, TJ Kieran, C Pappas, H Zeng, NM Vu, SS Lakdawala, TM Tumpey, and TR Maines |
Influenza |
2025 |
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Influenza |
2025 |
171 |
X Sun, JA Belser, ZN Li, N Brock, JA Pulit-Penaloza, TJ Kieran, C Pappas, H Zeng, JC Chang, PJ Carney, BL Bradley-Ferrell, J Stevens, TM Tumpey, MZ Levine, TR Maines. (2025). Effect of Prior Invluenza A(H1N1)pdm09 Virus Infection on Pathogenesis and Transmission of Influenza A(H5N1) Clade 2.3.4.4b Virus in Ferret Model. Emerging Infectious Diseases 31(3):458 https://doi.org/10.3201/eid3103.241489. |
| WS Lawrence, JE Peel, R de Winter, LL Ling, AG Nitti, AJ Peoples, R Shukla, HD MacGillavry, HS Heine, ME Mensel, EB Whorton, M Weingarth, K Lewis, and DE Hughes |
Bacillus anthracis |
2025 |
172 |
WS Lawrence, JE Peel, R de Winter, LL Ling, AG Nitti, AJ Peoples, R Shukla, HD MacGillavry, HS Heine, ME Mensel, EB Whorton, M Weingarth, K Lewis, and DE Hughes. (2025). Teixobactin: A resistance-evading antibiotic for treating anthrax. ACS Infectious Diseases 11(3):727 https://doi.org/10.1021/acsinfecdis.4c00835. |
| JE Peel, E Jardinella, Y Qu, JA Plante, BM Mitchell, JL Walker, RP Garofalo, SC Weaver, KS Plante, T Brasel, and WS Lawrence |
SARS-CoV-2 |
2025 |
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JE Peel, E Jardinella, Y Qu, JA Plante, BM Mitchell, JL Walker, RP Garofalo, SC Weaver, KS Plante, T Brasel, and WS Lawrence. (2025). Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens. American Journal of Infection Control S0196-6553 https://doi.org/10.1026/j.ajic.2025.02.008. |
| PB Kilgore, J Sha, EK Hendrix, BH Neil, WS Lawrence, JE Peel, L Hittle, J Woolston, A Sulakvelidze, JA Schwarz, and AK Chopra |
Yersinia pestis |
2024 |
174 |
PB Kilgore, J Sha, EK Hendrix, BH Neil, WS Lawrence, JE Peel, L Hittle, J Woolston, A Sulakvelidze, JA Schwarz, and AK Chopra. (2024). A bacteriophage cocktail targeting Yersinia pestis provides strong post-exposure protection in a rat pneumonic plague model. Microbiology Spectrum 12(11) https://doi.org/10.1128/spectrum.00942-24. |
| WS Lawrence, JE Peel, R Slayden, JW Peterson, WB Baze, ME Hensel, EB Whorton, DWC Beasley, JE Cummings, I Macias-Perez |
Bacillus anthracis |
2024 |
175 |
WS Lawrence, JE Peel, R Slayden, JW Peterson, WB Baze, ME Hensel, EB Whorton, DWC Beasley, JE Cummings, I Macias-Perez. (2024). Rapid in vitro activity of telavancin against Bacillus anthracis and in vivo protection against inhalation anthrax infection in the rabbit model. Antimicrobial Agents and Chemotherapy 68(7):e0011224 https://doi.org/10.1128/aac00112-24. |
| D Abelson, J Barajas, L Stuart, D Kim, A Marimuthu, C Hu, B Yamamoto, E Ailor, KJ Whaley, H Vu, KN Agans, V Borisevich, DJ Deer, NS Dobias, C Woolsey, AN Prasad, JE Peel, WS Lawrence, RW Cross, TW Geisbert, KA Fenton, and L Zeitlin |
Marburg virus |
2023 |
176 |
D Abelson, J Barajas, L Stuart, D Kim, A Marimuthu, C Hu, B Yamamoto, E Ailor, KJ Whaley, H Vu, KN Agans, V Borisevich, DJ Deer, NS Dobias, C Woolsey, AN Prasad, JE Peel, WS Lawrence, RW Cross, TW Geisbert, KA Fenton, and L Zeitlin. (2023). Long-term prophylaxis against aerosolized Marburg virus in non-human primates with an afucosylated monoclonal antibody. Journal of Infectious Diseases 228:S701 https://doi.org/10.1093/infdis/jiad278. |
| AN Prasad, KA Fenton, KN Agans, V Borisevich, C Woolsey, JE Comer, NS Dobias, JE Peel, DJ Deer, JB Geisbert, WS Lawrence, RW Cross, and TW Geisbert |
Ebolavirus |
2023 |
177 |
AN Prasad, KA Fenton, KN Agans, V Borisevich, C Woolsey, JE Comer, NS Dobias, JE Peel, DJ Deer, JB Geisbert, WS Lawrence, RW Cross, and TW Geisbert. (2023). Pathogenesis of aerosolized Ebola virus variant Makona in nonhuman primates. Journal of Infectious Diseases 228:S604 https://doi.org/10.1093/infdis/jiad137. |
| MM Shilman, G Bartolo, S Alameh, JW Peterson, WS Lawrence, JE Peel, SK Sivasubramani, DWC Beasley, CK Cote, ST Demons, SA Halasahoris, LL Miller, CP Klimko, JL Shoe, DP Fetterer, R McComb, CC Ho, KA Bradley, S Hartmann, ..., A Levitin, and J West |
Bacillus anthracis |
2021 |
178 |
MM Shilman, G Bartolo, S Alameh, JW Peterson, WS Lawrence, JE Peel, SK Sivasubramani, DWC Beasley, CK Cote, ST Demons, SA Halasahoris, LL Miller, CP Klimko, JL Shoe, DP Fetterer, R McComb, CC Ho, KA Bradley, S Hartmann, LW Cheng, M Chugnova, C Kao, J Tran, A Derbedrossian, L Zilbermintz, E Amali-Adekwu, A Levitin, and J West. (2021). In vivo activity of repurposed amodiaquine as a host-targeting therapy for the treatment of anthrax. ACH Infectious Diseases 7(8):2176 https://doi.org/10.1021/acsinfecdis.1c00190. |
| I Tretyakova, KS Plante, SL Rossi, WS Lawrence, JE Peel, S Gudjohnsen, E Wang, D Mirchandani, A Tibbens, TN Lamichhane, IS Lukashevich, JE Comer, SC Weaver, and P Pushko |
Alphavirus |
2020 |
179 |
I Tretyakova, KS Plante, SL Rossi, WS Lawrence, JE Peel, S Gudjohnsen, E Wang, D Mirchandani, A Tibbens, TN Lamichhane, IS Lukashevich, JE Comer, SC Weaver, and P Pushko. (2000). Venezuelan equine encephalitis vaccine with rearranged genome resists reversion and protects non-human primates from viremia after aerosol Challenge. Vaccine 38(17):3378 https://doi.org/10.1016/j.vaccine.2020.02.007. |
| J Sha, ML Kirtley, C Klages, TE Erova, M Telepnev, D Ponnusamy, EC Fitts, WB Baze, SK Sivasubramani, WS Lawrence, I Patrikeev, JE Peel, JA Andersson, EV Kozlova, BL Tiner, JW Peterson, D McWilliams, S Patel, E Rothe, VL Motin, and AK Chopra |
Yersinia pestis |
2016 |
180 |
J Sha, ML Kirtley, C Klages, TE Erova, M Telepnev, D Ponnusamy, EC Fitts, WB Baze, SK Sivasubramani, WS Lawrence, I Patrikeev, JE Peel, JA Andersson, EV Kozlova, BL Tiner, JW Peterson, D McWilliams, S Patel, E Rothe, VL Motin, and AK Chopra. (2016). A replication-defective human type-5 adenovirus-based trivalent vaccine confers complete protection against plague in mice and non-human primates. Clinical and Vaccine Immunology 23(7):586 https://doi.org/10.1128/CVI.00150-16. |
| J Yeager, K Beck, S Gardner, M McMann, S Wood, B Holland, E Keyser, C Davies, S Ratnesar-Shumate, A Haddrell, J Reid, R Thomas, and P Dabisch |
E coli |
2025 |
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| I Nicholls, O Onianwa, S Collins, A Spencer, S Parks, B Atkinson, and T Pottage |
SARS-CoV-2 |
2025 |
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| SM Baker, DW Settles, KR Celona, AB Shannon, C Davitt, K Hall, A Jain…CT Dao, J Mose, D Pociask, P Keim, K Russel-Lodrigue, CJ Roy, and LA Morici |
Burkholderia pseudomallei |
2025 |
183 |
SM Baker, DW Settles, KR Celona, AB Shannon, C Davitt, K Hall, A Jain…CT Dao, J Mose, D Pociask, P Keim, K Russel-Lodrigue, CJ Roy, and LA Morici. (2025). An outer membrane vesicle vaccine prevents lung pathology in a macaque model of pneumonic melioidosis. Nature Communications https://doi.org/10.1038/s41467-025-67213-6. |
| RE Ireland, A Nunez, W Butcher, C Davies, JD Blanchard, F Dayton, I Gonda, SV Harding, and M Nelson |
Francisella tularensis |
2025 |
184 |
RE Ireland, A Nunez, W Butcher, C Davies, JD Blanchard, F Dayton, I Gonda, SV Harding, and M Nelson. (2025). Inhaled liposomal ciprofloxacin protects against lethal tularemia in the common marmoset. Antimicrobial Agents and Chemotherapy e0123225 https://doi.org/10.1128/aac.01232-25. |
| HL Kutscher, M Tamblin, E Smith, A Shah, PO Kenney, and JL Reynolds |
Mycobacterium tuberculosis |
2026 |
185 |
HL Kutscher, M Tamblin, E Smith, A Shah, PO Kenney, and JL Reynolds. (2026). Repeated pulmonary dosing of B-glucan-chitosan-PLGA nanoparticles controls Mycobacterium tuberculosis in mice. Antimicrobial Agents and Chmotherapy 70:2 e01480-25 https://doi.org/10.1128/aac.01480-25. |
| Sun C, Gardner C, Lam LKM, Lundy J, O'Malley K, Luke T, Raviprakash K, Hartman AL, Crossland NA, Wu H, Jiao JA, Bausch C, Sullivan E, Reed DS, Klimstra WB |
Alphavirus |
2026 |
186 |
Sun C, Gardner C, Lam LKM, Lundy J, O'Malley K, Luke T, Raviprakash K, Hartman AL, Crossland NA, Wu H, Jiao JA, Bausch C, Sullivan E, Reed DS, Klimstra WB. A single dose of purified human antibody from transchromosomic bovines mitigates aerosolized Venezuelan equine encephalitis virus disease in cynomolgus macaques. PLoS One. 2026 Apr 27;21(4):e0347864. https://doi.org/10.1371/journal.pone.0347864. |
| Peel JE, Varghese AA, Paez RN, Chauhan S, Endsley JJ, Lawrence WS |
Mycobacterium tuberculosis |
2026 |
187 |
Peel JE, Varghese AA, Paez RN, Chauhan S, Endsley JJ, Lawrence WS. Airborne Mycobacterium tuberculosis inactivated by advanced photohydrolysis technology. Ann Clin Microbiol Antimicrob. 2026 Mar 4;25(1):17. https://doi.org/10.1186/s12941-026-00855-6. |
| Dabisch PA, Xu Z, Boydston JA, Solomon J, Bohannon JK, Yeager JJ, Taylor JR, Reeder RJ, Sayre P, Seidel J, Mollura DJ, Hevey MC, Jahrling PB, Lackemeyer MG |
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2017 |
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